Vol. 7, Issue 2, Part G (2025)

Venous Thromboembolism (VTE), which includes deep vein thrombosis and pulmonary embolism, remains a significant global health burden due to its high rates of illness and death. The primary approach to both treating and preventing VTE is anticoagulation. This review summarizes current research on the effectiveness and safety of major anticoagulant classes such as heparins, vitamin K antagonists, and direct oral anticoagulants. It highlights their mechanisms, key clinical evidence, and recent developments in VTE care, emphasizing the need to balance the benefits of preventing clot formation with the risk of bleeding complications.