Vol. 7, Issue 2, Part F (2025)

Medication adherence is crucial for managing chronic illness, yet non-adherence is still common worldwide.
Objective: To review the barriers to adherence, evaluate interventions, and assess outcomes.
Methods: This is a narrative review that synthesizes systematic reviews, RCTs, and meta-analyses from 2016 to 2025.
Results: Barriers include issues related to patients, therapy, conditions, socioeconomic factors, and health systems. Evidence-based interventions include simplifying regimens, pharmacist-led programs, SMS reminders, apps, electronic monitoring, and motivational interviewing. Improved adherence highlights better disease control and lower costs.
Conclusion: Tailored, multicomponent interventions are most effective. Future research should focus on ensuring long-term sustainability and equity.