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International Journal of Pharmacology and Clinical Research
Peer Reviewed Journal

Vol. 7, Issue 2, Part D (2025)

Neuroprotective effects of Bacopa monnieri and Withania somnifera in Alzheimer's disease

Author(s):

Padmini Sharma, Avneet Gupta, Sidhant Sharma, Jyoti Kashyap, Varun Kumar and Yogesh Kuamr

Abstract:

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline, memory impairment, and behavioral changes. Traditional medicinal plants, particularly Bacopa monnieri and Withania somnifera, have been extensively studied for their neuroprotective properties. This review examines their pharmacological mechanisms, clinical evidence, and therapeutic potential in AD management, highlighting roles in oxidative stress modulation, anti-inflammatory effects, amyloid clearance, and cognitive enhancement. Cumulative evidence suggests these herbs could serve as complementary or adjunctive therapies in AD, though further rigorous clinical trials are warranted.

Pages: 277-280  |  612 Views  358 Downloads


International Journal of Pharmacology and Clinical Research
How to cite this article:
Padmini Sharma, Avneet Gupta, Sidhant Sharma, Jyoti Kashyap, Varun Kumar and Yogesh Kuamr. Neuroprotective effects of Bacopa monnieri and Withania somnifera in Alzheimer's disease. Int. J. Pharmacol. Clin. Res. 2025;7(2):277-280. DOI: 10.33545/26647613.2025.v7.i2d.119
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