Vol. 7, Issue 2, Part B (2025)

The study was conducted using 21 male laboratory rats of average mean weight of 190 g. These rats were further subdivided into three parts where seven were used as the normal (control) group after which seven were infected with Ascaris lumbricoides and the rest infected and treated using the alcoholic extract of Artemisia herba-alba (AHA's AE) also known as AEs. Several physiologic and immunologic measurements were analyzed such as intestinal hormones (CCK and SST) and immunologic markers (IgE, IL-4, IL-5, IL-10, IL-13 and IFN-γ). As a result a clear rise in the levels of hormones was evident. The levels of CCK were 127.31, 207.75, and 178.27 pg/ml, whereas SST equal 46.80, 105.66 and 77.69 pg/ml, respectively. Correspondingly, the immunological markers in the infected and in rats treated with AHA's AE were on an increased scale as compared to the normal group. The IgE levels were 150.65, 370.21, 246.76 pg/ml; IL- 4 levels measured 70.63, 117.32 and 94.59 pg/ml; IL-5 levels attained to 44.49, 121.22 and 80.61 pg/ml; IL-10 levels were 23.53, 100.53, 67.37 pg/ml; IL-13 levels were 67.22, 200.40, and 188.58 pg/ml; and IFN-γ levels were 54.27, 162.15, and 113.44 pg/ml, respectively.