Vol. 6, Issue 2, Part A (2024)

Medicinal plants have long been recognized for their extensive therapeutic potential, providing effective natural remedies for managing various health conditions, including wound healing. Herbal formulations have played a vital role in traditional medicine worldwide, offering solutions for promoting tissue repair and regeneration. In the present study, the wound-healing activity of the hydroalcoholic extract of Plumeria acuminata was evaluated, focusing on its effects in excision and incision wound models in Wistar albino rats. The research assessed critical parameters such as wound contraction rate, epithelialization time, and histopathological changes to determine the efficacy of the plant extract. The results indicate that Plumeria acuminata hydroalcoholic extract significantly enhances wound healing by accelerating tissue repair, reducing inflammation, and promoting collagen synthesis. These findings underscore the potential of Plumeria acuminata as a natural therapeutic agent for wound management, providing a safer and more effective alternative to synthetic wound-healing agents. Further studies are recommended to explore its broader pharmacological activities, bioactive constituents, and underlying mechanisms to establish its clinical utility for wound care and tissue regeneration.