Cardiovascular drugs and pharmacovigilance-a comprehensive study in India
Prashant Ashok Pawar, Tushar Atmaram Deshmukh, Jitendra B Naik
Cardiovascular diseases (CVD) are one of the leading causes of non-communicable disease-related deaths globally. Patients with cardiovascular diseases are often prescribed multiple drugs and have a higher risk for developing more adverse drug reactions due to polypharmacy. Adverse drug reactions (ADRs) can result in several consequences, ranging from allergic reactions to permanent harm thereby causing morbidity and mortality leading to an increase in the health care cost. The main objective of the present study was to assess the prevalence of adverse drug reactions due to cardiovascular drugs. The common ADRs due to cardiovascular drugs can be reduced by improving the prescription pattern. Cough, gastritis, fatigue, and myalgia by enalapril, aspirin, β-blockers, and atorvastatin respectively were found to be the most commonly reported ADRs among the cardiovascular drugs. This review highlights the importance of systematic evaluation of adverse drug reactions and highlights the new directions that pharmacovigilance has taken.
Prashant Ashok Pawar, Tushar Atmaram Deshmukh, Jitendra B Naik. Cardiovascular drugs and pharmacovigilance-a comprehensive study in India. International Journal of Pharmacology and Clinical Research, Volume 4, Issue 1, 2022, Pages 1-6